May 29, 2024
Diaconescu A.O., Karvelis P., Hauke D.J.


Barnby et al. investigated the effects of haloperidol, a D2/D3 dopamine antagonist, on social attributions. Using computational modeling, they demonstrate that haloperidol increases belief flexibility, reducing paranoia-like interpretations by enhancing sensitivity to social context and reducing self-relevant perspective taking, offering a mechanistic explanation for its therapeutic potential in schizophrenia.

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